2-(4-(三氟甲基)苯基)-3,5,7,8-四氢-4H-硫代吡喃并[4,3-d]嘧啶-4-酮
XAV-939
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Product Overview
Product Name XAV-939
CAS284028-89-3
FormulaC14H11F3N2OS
MW312.31
Appearance White to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.


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