(2E)-N-[4-[3-氯-4-(2-吡啶基甲氧基)苯胺基]-3-氰基-7-乙氧基-6-喹啉基]-4-(二甲氨基)-2-丁烯酰胺;来那替尼
Neratinib (Synonyms: HKI-272)
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Product Overview
Product Name Neratinib (Synonyms: HKI-272)
CAS698387-09-6
FormulaC30H29ClN6O3
MW557.04
MDLMFCD09752958
AppearancePale yellow to white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Neratinib is a highly selective inhibitor of HER2 and EGFR, demonstrating IC50 values of 59 nM and 92 nM in cell-free assays, respectively. It weakly inhibits KDR and Src, while showing no significant inhibition against Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf, and c-Met. Tags: buy Neratinib | Neratinib supplier | purchase Neratinib | Neratinib cost | Neratinib manufacturer | order Neratinib | Neratinib distributor

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History
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