Product Name | WYE-132(WYE-125132) |
---|---|
CAS | 1144068-46-1 |
Formula | C27H33N7O4 |
MW | 519.60 |
Appearance | White to gray powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
WYE-125132 (also known as WYE 132) is a novel, highly potent, selective and ATP-competitive inhibitor of mTOR (mammalian target of rapamycin) with potential antitumor activity. It inhibits mTOR with an IC50 of 0.19 nM; It exhibits high selectivity for mTOR over PI3K and inhibits mTOR with an IC50 of 0.19 nM.
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