Product Name | SIS3 HCl |
---|---|
CAS | 521984-48-5 |
Formula | C28H28ClN3O3 |
MW | 489.99 |
Appearance | Light yellow to yellow powder |
Storage condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
SIS3 HCl, a novel specific inhibitor of Smad3, inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways.
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