阿立他滨 | 阿普瑞西他滨
Apricitabine | SPD754 | AVX754
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CAS No.:
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1 mg 5 mg
Product Availability
3-5days
Price
$168.00
Member price
Product Availability
3-5days
Price
$388.00
Member price
Quantity
- +
Product Overview
Product Name Apricitabine | SPD754 | AVX754
CAS160707-69-7
FormulaC8H11N3O3S
MW229.26
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Product details

Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β and γ with Ki values of 300 μM, 12 μM and 112.25 μM, respectively. Apricitabine has shown good antiretroviral therapeutic efficacy in antiretroviral HIV-infected patients, with good tolerability and low selective resistance.


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History
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