Product Name | Tandutinib | MLN518 | CT53518 |
---|---|
CAS | 387867-13-2 |
Formula | C₃₁H₄₂N₆O₄ |
MW | 562.7 |
Appearance | Yellowish powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
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