(S)-2-(6-(4-氯苯基)-1-甲基-4H-苯并[c]异恶唑并[4,5-e]氮杂环庚烷-4-基)乙酰胺
Pelabresib (Synonyms: CPI-0610)
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Product Overview
Product Name Pelabresib (Synonyms: CPI-0610)
CAS1380087-89-7
FormulaC20H16ClN3O2
MW365.81
MDLMFCD28144505
AppearanceWhite to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Pelabresib (CPI-0610) is a potent and selective benzoisoxazoloazepine BET bromodomain inhibitor with an IC50 of 39 nM for BRD4-BD1 in TR-FRET assay and currently undergoing human clinical trials for hematological malignancies. CPI-0610 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.

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History
Pelabresib (Synonyms: CPI-0610)
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