Product Name | Brigatinib | AP-26113 |
---|---|
CAS | 1197953-54-0 |
Formula | C29H39ClN7O2P |
MW | 584.09 |
Appearance | White to light yellow powder |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Brigatinib is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.
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