Product Name | ABT-888(Veliparib) |
---|---|
CAS | 912444-00-9 |
Formula | C13H16N4O |
MW | 244.29 |
Appearance | White solid |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3.
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