Product Name | Ponatinib | AP24534 |
---|---|
CAS | 943319-70-8 |
Formula | C29H27F3N6O |
MW | 532.56 |
Melting point | >160 °C |
Appearance | Light yellow to yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
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