塞卡替尼
Saracatinib (AZD0530)
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In-stock
Price
$106.00
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Product Availability
In-stock
Price
$166.00
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Product Availability
3-5days
Price
$186.00
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Product Availability
3-5days
Price
$278.00
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Product Overview
Product Name Saracatinib (AZD0530)
CAS379231-04-6
FormulaC27H32ClN5O5
MW542.03
AppearanceWhite to light yellow powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

 Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival.

Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases.


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History
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