雷帕霉素 | 西罗莫司
Rapamycin | Sirolimus | AY-22989 | NSC-2260804
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Product Name Rapamycin | Sirolimus | AY-22989 | NSC-2260804
CAS53123-88-9
FormulaC51H79NO13
MW914.18
AppearanceWhite to off-white powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.


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History
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