(1R,4S,5S,6S)-4-氨基-2-硫杂双环[3.1.0]己烷-4,6-二甲酸 2,2-二氧化物
LY404039 (Synonyms: pomaglumetad;LY2140023)
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Product Name LY404039 (Synonyms: pomaglumetad;LY2140023)
CAS635318-11-5
FormulaC₇H₉NO₆S
MW235.21
AppearanceWhite to gray powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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LY404039 is a potent, selective and orally active mGluR2 and mGluR3 agonist with Kis of 149 nM and 92 nM for recombinant human mGluR2 and mGluR3, respectively. LY404039 shows >100-fold selectivity for mGluR2/3 over other receptors/transproters. LY404039 has antipsychotic and anxiolytic effects.
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History
LY404039 (Synonyms: pomaglumetad;LY2140023)
Bictegravir (Synonyms: GS-9883)
U0126 (Synonyms: MEK1/2抑制剂 )