Product Name | Crizotinib (PF-02341066) |
---|---|
CAS | 877399-52-5 |
Formula | C21H22Cl2FN5O |
MW | 450.34 |
MDL | MFCD12407409 |
Appearance | White to light brown powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Crizotinib (PF-02341066) is a potent, orally bioavailable small molecule inhibitor of c-Met and ALK that is bioavailable when taken orally. In assays based on cells, it inhibits c-Met and ALK with IC50 values of 11 nM and 24 nM, respectively.
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