Linsitinib (OSI-906)
Linsitinib (OSI-906)
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Product Availability
3-5days
Price
$125.00
Member price
Product Availability
3-5days
Price
$245.00
Member price
Product Availability
3-5days
Price
$400.00
Member price
Quantity
- +
Product Overview
Product Name Linsitinib (OSI-906)
CAS867160-71-2
FormulaC26H23N5O
MW421.49
AppearanceWhite to yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

Linsitinib (formerly OSI-906; OSI 906) is a firs-in-class, ATP-competitive and orally bioavailable dual inhibitor of and insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) with potential antitumor activity. It exhibits modest potency against InsR with an IC50 of 75 nM, and it has no activity against other kinases like Abl, ALK, BTK, EGFR, FGFR1/2, PKA, and so on. In cell-free assays, it inhibits IGF-1R with an IC50 of 35 nM.

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Linsitinib (OSI-906)