Linsitinib (OSI-906)
Linsitinib (OSI-906)
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
1 mg 5 mg 10 mg
Product Availability
3-5days
Price
$125.00
Member price
Product Availability
3-5days
Price
$245.00
Member price
Product Availability
3-5days
Price
$400.00
Member price
Quantity
- +
Product Overview
Product Name Linsitinib (OSI-906)
CAS867160-71-2
FormulaC26H23N5O
MW421.49
AppearanceWhite to yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
Product details

Linsitinib (formerly OSI-906; OSI 906) is a firs-in-class, ATP-competitive and orally bioavailable dual inhibitor of and insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) with potential antitumor activity. It exhibits modest potency against InsR with an IC50 of 75 nM, and it has no activity against other kinases like Abl, ALK, BTK, EGFR, FGFR1/2, PKA, and so on. In cell-free assays, it inhibits IGF-1R with an IC50 of 35 nM.

Related literature
Related
Sorry, no related items
History
Risdiplam (Synonyms: RG7916; RO7034067)
Anacetrapib (MK-0859)
Linsitinib (OSI-906)
Nelarabine (Synonyms: 506U78; GW 506U78; Nelzarabine)
Elafibranor | GFT505
Pyridostatin (Synonyms: RR82)
Emibetuzumab (Anti-HGFR / c-Met)
Crizotinib (Synonyms: PF-02341066)
Astragaloside IV
Rapamycin (Synonyms: Sirolimus; AY-22989; NSC-2260804)