PF-03814735
PF-03814735
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3-5days
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$160.00
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Product Availability
3-5days
Price
$457.00
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Product Availability
3-5days
Price
$460.00
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Product Overview
Product Name PF-03814735
CAS942487-16-3
FormulaC23H25F3N6O2
MW474.48
AppearanceWhite to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

PF-03814735 (PF03814735) is a reversible, orally bioavailable, and ATP-competitive inhibitor of Aurora A/B kinases with potential antitumor activity. It inhibits Aurora A/B with IC50of 0.8 nM and 5 nM, respectively. PF-03814735 showed less potency against Flt3, FAK, TrkA, Met and FGFR1. It exhibits potent in vitro antiproliferative activity and high in vivo antitumor efficacy.

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History
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