Product Name | Lobeline hydrochloride(α-Lobeline hydrochloride; L-Lobeline hydrochloride) |
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CAS | 134-63-4 |
Formula | C22H28ClNO2 |
MW | 373.92 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Lobeline hydrochloride, an alkaloid and nonstimulant medication that can alter dopamine uptake in brain, is a novel and potent a nicotinic receptor agonist and VMAT2 ligand, which stimulates dopamine release, and inhibits the reuptake of dopamine and serotonin, acting as a mixed agonist-antagonist at nicotinic acetylcholine receptors and antagonist at µ-opioid receptors.
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