阿迪普隆
AdipoRon (Synonyms: SC-396658)
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Product Availability
3-5days
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$120.00
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Product Availability
3-5days
Price
$338.00
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Product Availability
3-5days
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$720.00
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Product Overview
Product Name AdipoRon (Synonyms: SC-396658)
CAS924416-43-3
FormulaC27H28N2O3
MW428.52
AppearanceOff-white to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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AdipoRon (also known as SC-396658) is a novel, first-in-class, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively. AdipoRon (5-50 μM) increased AMPK phosphorylation via AdipoR1 in a dose-dependent way. Also, AdipoRon replenished adiponectin-stimulated AMPK phosphorylation. In C2C12 myotubes, AdipoRon increased PGC-1α expression and mitochondrial DNA content in a Ca2+- and dose-dependent way.
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History
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