卡培他滨
Capecitabine | RO 09-1978 | Xeloda
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name Capecitabine | RO 09-1978 | Xeloda
CAS154361-50-9
FormulaC15H22FN3O6
MW359.35
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Security information
Product details

Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.


Related literature
Related
Sorry, no related items
History
Capecitabine | RO 09-1978 | Xeloda
Vasicinone | (-)-Vasicinone
Theaflavine Gallate
PF-477736 | PF-736 | PF-00477736
Chrysene
Pemigatinib (Synonyms: INCB054828)
Iloprost
Amifostine
Nelarabine | 506U78 | GW 506U78 | Arranon