噁拉戈利钠
Elagolix Sodium; NBI 56418NA; NBI-56418 sodium
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5 mg 10 mg
Product Availability
3-5days
Price
$120.00
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Product Availability
3-5days
Price
$160.00
Member price
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- +
Product Overview
Product Name Elagolix Sodium; NBI 56418NA; NBI-56418 sodium
CAS832720-36-2
FormulaC32H29F5N3NaO5
MW653.57
AppearanceWhite to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Elagolix sodium (NBI56418; ABT-620; Orilissa), the sodium salt of Elagolix, is an orally bioavailable and small molecule antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM) approved on 7/23/2018 by FDA for the management of moderate to severe pain associated with endometriosis. Elagolix is a short-acting GnRH antagonist that suppresses ovarian estrogen production in a dose-dependent manner, meaning that higher doses result in full suppression while lower doses only cause partial suppression. Elagolix's non-peptide structure and oral bioavailability make it the leader of a new class of GnRH inhibitors known as second-generation inhibitors.

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Elagolix Sodium; NBI 56418NA; NBI-56418 sodium