| Product Name | NVP-BEZ235 (Synonyms: Dactolisib; BEZ235) |
|---|---|
| CAS | 915019-65-7 |
| Formula | C30H23N5O |
| MW | 469.54 |
| MDL | MFCD10565944 |
| Appearance | White to light yellow powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110α, 5 nM for p110γ, 7 nM for p110δ, 75 nM for p110β, and 20.7 nM for mTOR.
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