2-甲基-2-(4-(3-甲基-2-氧代-8-(喹啉-3-基)-2,3-二氢-1H-咪唑并[4,5-c]喹啉-1-基)苯基)丙腈; 达克利司
NVP-BEZ235 (Synonyms: Dactolisib; BEZ235)
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Product Overview
Product Name NVP-BEZ235 (Synonyms: Dactolisib; BEZ235)
CAS915019-65-7
FormulaC30H23N5O
MW469.54
MDLMFCD10565944
AppearanceWhite to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Product details

Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110α, 5 nM for p110γ, 7 nM for p110δ, 75 nM for p110β, and 20.7 nM for mTOR.


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History
Tamoxifen
Gemcitabine Hydrochloride | Gemcitabine HCl | LY 188011 hydrochloride | NSC 613327 HCl
NVP-BEZ235 (Synonyms: Dactolisib; BEZ235)
BMS-1166 hydrochloride
Stachydrine Hydrochloride
(R)-Benzyl 3-hydroxypiperidine-1-carboxylate
Sarcandrone A
(-)-(S)-Equol | AUS 131 | SE 5OH
Luminol sodium salt; Luminol monosodium salt
Inavolisib | GDC-0077 | RG6114 | RO-7113755