特司林
Tesirine | SG3249
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1 mg 5 mg
Product Availability
3-5days
Price
$5266.00
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Product Availability
3-5days
Price
$11590.00
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Product Overview
Product Name Tesirine | SG3249
CAS1595275-62-9
FormulaC75H101N9O23
MW1496.65
Appearance White to light yellow powder
Storage conditionAvoid light, nitrogen, -20 ℃
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Product details

Tesirine (SG-3249; SG3249), cathepsin B-cleavable valine-alanine pyrrolobenzodiazepine (PBD) dimer used as an antibody-drug conjugate (ADC) payload; Tesirine was designed to combine the potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. Rovalpituzumab tesirine is a first-in-class ADC directed against delta-like protein 3 (DLL3), a novel target identified in tumour-initiating cells and expressed in small-cell lung cancer.

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Tesirine | SG3249