N-(5-(3,5-二氟苄基)-1H-吲唑-3-基)-4-(4-甲基哌嗪-1-基)-2-((四氢-2H-吡喃-4-基)氨基)苯甲酰胺;恩曲替尼
Entrectinib (Synonyms: NMS-E628; RXDX-101)
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Product Name Entrectinib (Synonyms: NMS-E628; RXDX-101)
CAS1108743-60-7
FormulaC31H34F2N6O2
MW560.64
MDLMFCD28129099
AppearanceOff-white to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Entrectinib (formerly also known as NMS-E628; RXDX-101) is a potent and orally bioavailable small molecule inhibitor of TrkA, TrkB, TrkC, ROS1 and ALK with potential antitumor activity.

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Entrectinib (Synonyms: NMS-E628; RXDX-101)