克拉生坦
Clazosentan
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Product Overview
Product Name Clazosentan
CAS180384-56-9
FormulaC25H23N9O6S
MW577.57
AppearanceOff-white to light yellow powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Clazosenta (Ro 61-1790, VML-588 and AXV-034) is a novel and highly potent endothelin A antagonist which improves cerebral blood flow and behavior after traumatic brain injury. Clazosentan is being developed in clinical trials for the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH) by Actelion Pharmaceuticals.Clazosentant decreases and reverses cerebral vasospasm after experimental SAH. Clazosentanthas been shown to reduce vasospasm after aneurysmal subarachnoid hemorrhage (aSAH).

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Clazosentan