沙芬酰胺
Safinamide (FCE 26743; EMD 1195686)
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Product Overview
Product Name Safinamide (FCE 26743; EMD 1195686)
CAS133865-89-1
FormulaC17H19FN2O2
MW302.34
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Safinamide (EMD-1195686, PNU-15774E) is an orally active, selective, reversible monoamine oxidase-B inhibitor with both dopaminergic and non-dopaminergic (glutamatergic) properties. The IC50 value of safinamide for MAO-B is 98 nM.

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History
Safinamide (FCE 26743; EMD 1195686)
1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone;GSK2606414 (Synonyms: GSK 2606414)