Product Name | Deruxtecan | DS-8201a | exatecan derivative | DX 8951; |
---|---|
CAS | 1599440-13-7 |
Formula | C52H56FN9O13 |
MW | 1,034.05 |
MDL | MFCD31657445 |
Appearance | White to yellow powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).
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