Product Name | Selonsertib | GS-4997 | Selonsertib (free base) |
---|---|
CAS | 1448428-04-3 |
Formula | C24H24FN7O |
MW | 445.5 |
Appearance | Off-white to light yellow powder |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Selonsertib (GS-4997), an orally bioavailable, selective apoptosis signal-regulating kinase 1 (ASK1) inhibitor with a pIC50 of 8.3, has been evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis.
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