(S)-2-(6-(4-氯苯基)-8-甲氧基-1-甲基-4H-苯并[f][1,2,4]三唑[4,3-a][1,4]二氮杂卓-4-基)-N-乙基乙酰胺 |I-BET762 | GSK525762 | GSK525762A
Molibresib (Synonyms: I-BET762; GSK525762; GSK525762A;I-BET-762)
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Product Overview
Product Name Molibresib (Synonyms: I-BET762; GSK525762; GSK525762A;I-BET-762)
CAS1260907-17-2
FormulaC22H22ClN5O2
MW423.90
MDLMFCD22417091
AppearanceOff-white to yellow powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Molibresib (I-BET-762, GSK525762, GSK525762A) is an inhibitor for BET proteins with IC50 of ~35 nM in a cell-free assay, suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation, highly selective over other bromodomain-containing proteins.
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Molibresib besylate (Synonyms: GSK 525762C; I-BET 762 besylate)
History
Molibresib (Synonyms: I-BET762; GSK525762; GSK525762A;I-BET-762)
Naringin Dihydrochalcone (Synonyms: Naringin DC)
PSMA-ligand-1 | Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid
Timosaponin A3 | Timosaponin AIII
Spinosin
Sequosempervirin D
Solasurine
Ehretioside B
Betulinic Acid
Finerenone (BAY94-8862)