BIX-01294
BIX-01294
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Product Overview
Product Name BIX-01294
CAS935693-62-2
FormulaC28H38N6O2
MW490.64
AppearanceWhite to off-white powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4℃, long-term (months to years) storage at -20 ℃.
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Product details

BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells。


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BIX-01294 trihydrochloride | BIX01294 triHCl
History
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3CzClIPN