BIX-01294三盐酸盐
BIX-01294 trihydrochloride | BIX01294 triHCl
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Product Name BIX-01294 trihydrochloride | BIX01294 triHCl
CAS1392399-03-9
FormulaC28H41Cl3N6O2
MW600.02
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Product details

BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in a cell-free assay, reduces H3K9me2 of bulk histones, also weakly inhibits GLP (primarily H3K9me3), no significant activity observed at other histone methyltransferases. BIX01294 induces autophagy. BIX01294 also inhibits H3K36 methylation by oncoproteins NSD1, NSD2 and NSD3.


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