Cilofexor(GS-9674)
Cilofexor(GS-9674)
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Product Overview
Product Name Cilofexor(GS-9674)
CAS1418274-28-8
FormulaC28H22Cl3N3O5
MW586.85
AppearanceOff-white to light yellow powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Cilofexor, formerly known as GS-9674, is a farnesoid X receptor (FXR) agonist. The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC. In clinical study, cilofexor was well tolerated and led to significant improvements in liver biochemistries and markers of cholestasis in patients with PSC.

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History
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