Product Name | Orantinib | SU 6668 | TSU-68 |
---|---|
CAS | 252916-29-3 |
Formula | C18H18N2O3 |
MW | 310.35 |
Appearance | Yellow to orange powder |
Storage condition | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.
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