(3R,4R) 替凡替尼 (ARQ 197), 肝细胞生长因子受体抑制剂 | 替万替尼
Tivantinib | ARQ-197
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Product Name Tivantinib | ARQ-197
CAS905854-02-6
FormulaC23H19N3O2
MW369.42
AppearanceLight brown to brown powder
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Product details

Tivantinib is the first non-ATP-competitive c-Met inhibitor with Ki of 0.355 μM in a cell-free assay, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. Tivantinib (ARQ 197) induces a G2/M arrest and apoptosis.


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History
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