PF-477736 | PF-736 | PF-00477736
PF-477736 | PF-736 | PF-00477736
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5 mg 10 mg
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3-5days
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$226.00
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3-5days
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$336.00
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Product Overview
Product Name PF-477736 | PF-736 | PF-00477736
CAS952021-60-2
FormulaC22H25N7O2
MW419.48
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Product details

PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.


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History
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PF-477736 | PF-736 | PF-00477736
MK-2206 dihydrochloride | MK-2206 ·2HCl