顺式-4-[(4-氯苯基)磺酰基]-4-(2,5-二氟苯基)环己烷丙酸
MK-0752
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CAS No.:
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Size
1 mg 5 mg
Product Availability
3-5days
Price
$148.00
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Product Availability
3-5days
Price
$368.00
Member price
Quantity
- +
Product Overview
Product Name MK-0752
CAS471905-41-6
FormulaC21H21ClF2O4S
MW442.91
MDLMFCD21608529
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Product details

MK-0752 is a potent, orally active and specific γ-secretase inhibitor, showing dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells. MK-0752 crosses the blood-brain barrier. MK-0752 reduces newly generated CNS Aβ in vivo.


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History
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