Product Name | Ropivacaine hydrochloride |
---|---|
CAS | 98717-15-8 |
Formula | C17H26N2O·HCl |
MW | 310.86 | 274.41(free) |
Appearance | White to off-white powder |
Storage condition | 4°C, sealed storage, away from moisture |
Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is widely used for neuropathic pain management in vivo.
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