(R)-2-((6-(苄基氨基)-9-异丙基-9H-嘌呤-2-基)氨基)丁-1-醇
(R)-Roscovitine (Synonyms: Seliciclib; CYC202,细胞周期蛋白B激酶抑制剂;塞利西利)
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Product Name (R)-Roscovitine (Synonyms: Seliciclib; CYC202,细胞周期蛋白B激酶抑制剂;塞利西利)
CAS186692-46-6
FormulaC19H26N6O
MW354.45
MDLMFCD02266401
AppearanceWhite to off-white powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Roscovitine is a potent and selective CDK inhibitor for Cdc2CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. 

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(R)-Roscovitine (Synonyms: Seliciclib; CYC202,细胞周期蛋白B激酶抑制剂;塞利西利)