CX-5461 dihydrochloride
CX-5461 dihydrochloride
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name CX-5461 dihydrochloride
CASN/A
FormulaC27H27N7O2S·2HCl
MW586.54 | 513.62(free)
AppearanceLight yellow to yellow powder
Storage condition4°C, sealed storage, away from moisture
Security information
Product details

CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).


Related
CX-5461 | Pidnarulex
History
D-Luciferin sodium salt
CX-5461 dihydrochloride
Rupatadine (Synonyms: UR-12592)
Hydroxyurea (Hydroxycarbamide)
Lurbinectedin (Synonyms: PM01183; LY-01017; Tryptamicidin; PM-1183)
D-Isoleucine (Synonyms: (R)-Isoleucine)
Elagolix Sodium; NBI 56418NA; NBI-56418 sodium