CX-5461 dihydrochloride
CX-5461 dihydrochloride
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Product Overview
Product Name CX-5461 dihydrochloride
CASN/A
FormulaC27H27N7O2S·2HCl
MW586.54 | 513.62(free)
AppearanceLight yellow to yellow powder
Storage condition4°C, sealed storage, away from moisture
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Product details

CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).


Related
CX-5461 | Pidnarulex
History
Lixisenatide
Ketanserin tartrate | R41468 tartrate
CX-5461 dihydrochloride
Dinoprost Tromethamine Salt | Dinoprost Trometamol | Prostaglandin F2a tromethamine salt | PGF2α THAM | Prostaglandin F2α THAM