CX-5461 dihydrochloride
CX-5461 dihydrochloride
ChemLeader
Catalog No:
CAS No.:
MDLNo:
Formula:
MW:
Size
Quantity
- +
Product Overview
Product Name CX-5461 dihydrochloride
CASN/A
FormulaC27H27N7O2S·2HCl
MW586.54 | 513.62(free)
AppearanceLight yellow to yellow powder
Storage condition4°C, sealed storage, away from moisture
Security information
Product details

CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).


Related
CX-5461 | Pidnarulex
History
IBT6A | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine;(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Octreotide Acetate (Synonyms: SMS 201-995 acetate)
Oxytocin Acetate
Terbinafine lactate | TDT 067 lactate
CX-5461 dihydrochloride
Leuprolide
Sergliflozin etabonate | GW-869682X
Anti-CD30 (brentuximab vedotin biosimilar) mAb
Dronedarone Hydrochloride
Anti-Human CD3xCD20 Bispecific Antibody (Mosunetuzumab; BTCT-4465A; R07030816;CD20-TDB; RG7828; CD20 CD3 bispecific antibody.)