| Product Name | Tovinontrine (Synonyms: IMR-687) |
|---|---|
| CAS | 2062661-53-2 |
| Formula | C21H26N6O2 |
| MW | 394.47 |
| MDL | MFCD34567171 |
| Appearance | White to off-white powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease. IC50s are 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively.
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