Product Name | Obicetrapib (Synonyms: TA-8995; DEZ-001) |
---|---|
CAS | 866399-87-3 |
Formula | C32H31F9N4O5 |
MW | 722.60 |
MDL | MFCD30533470 |
Appearance | White to light yellow powder |
Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
Obicetrapib, also known as AMG-899, TA-8995, and DEX-001, is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial effect for cardiovascular disease risk reduction. TA-8995 dose dependently increased not only total and non-ABCA1-specific CEC but also ABCA1-specific CEC and preBeta-1 HDL particle levels.
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