N-((3S,4S)-3-((6-(2,6-二氯-3,5-二甲氧基苯基)喹唑啉-2-基)氨基)四氢-2H-吡喃-4-基)丙烯酰胺
Fisogatinib (Synonyms: BLU-554)
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3-5 days
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Product Overview
Product Name Fisogatinib (Synonyms: BLU-554)
CAS1707289-21-1
FormulaC24H24Cl2N4O4
MW503.38
MDLMFCD30496704
AppearanceWhite to light yellow powder
Storage conditionStore short-term at 0-4°C or long-term at -20°C in a dry, dark place.
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Product details

Fisogatinib (BLU-554) is a potent and highly selective oral FGFR4 inhibitor with an IC50 of 5 nM, demonstrating significant anti-tumor activity in HCC models reliant on FGFR4 signaling.Its IC50 values for FGFR1-3 are in the range of 624-2203 nM, highlighting its selectivity over other FGFR isoforms.

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History
Fisogatinib (Synonyms: BLU-554)
Gemcitabine (Synonyms: LY 188011;Gemcitabine Base;NSC 613327)