7-甲基-2-((7-甲基-[1,2,4]三唑并[1,5-a]吡啶-6-基)氨基)-9-(四氢-2H-吡喃-4-基)-7H-嘌呤-8(9H)-酮
AZD-7648
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3-5 days
Price
$98.00
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3-5 days
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3-5 days
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$236.00
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3-5 days
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$376.00
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Product Overview
Product Name AZD-7648
CAS2230820-11-6
FormulaC18H20N8O2
MW380.40
MDLMFCD32062688
AppearanceWhite to yellow powder
Storage conditionStore short-term at 0-4°C or long-term at -20°C in a dry, dark place.
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Product details

AZD-7648 is a potent, orally active, and selective DNA-PK inhibitor with an IC50 of 0.6 nM, demonstrating significant antitumor activity.This compound induces apoptosis and enhances the effects of radiation and chemotherapy, making it a promising therapeutic agent for myeloid leukemias.In addition to its cytotoxic effects, AZD-7648 also triggers cell cycle arrest, further contributing to its antitumor properties.

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History
Shoreic acid
AZD-7648
Anti-CD33 (gemtuzumab ozogamicin biosimilar) mAb