Product Name | Pelitinib (Synonyms: EKB-569; WAY-EKB 569) |
---|---|
CAS | 257933-82-7 |
Formula | C24H23ClFN5O2 |
MW | 467.92 |
MDL | MFCD09837868 |
Appearance | White to off-white powder |
Storage condition | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
Pelitinib (EKB-569) is a potent, irreversible EGFR inhibitor with an IC50 of 38.5 nM, displaying selectivity over Src, MEK/ERK, and ErbB2 with respective IC50s of 282 nM, 800 nM, and 1255 nM.
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