5-(4-氯苯基)-N-(3,5-二甲氧基苯基)呋喃-2-甲酰胺
A-803467
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Product Name A-803467
CAS944261-79-4
FormulaC19H16NO4Cl
MW357.79
MDLMFCD10574689
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A-803467 is a potent and selective tetrodotoxin-resistant Nav1.8 sodium channel blocker (IC50=8 nM). A-803467 has shown significant anti-nociception in neuropathic and inflammatory pain models. A-803467 enhances the chemosensitivity of conventional anticancer agents through interaction with the ATP-binding cassette subfamily G member 2 (ABCG2) transporter.

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