依洛尤单抗; 依伏库单抗
Anti-Human PCSK9 Monoclonal Antibody(Evolocumab); AMG 145
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1 mg 5 mg 10 mg 50 mg 100 mg
Product Availability
3-5days
Price
$600.00
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Product Availability
3-5days
Price
$1600.00
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3-5days
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$2800.00
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3-5days
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$13000.00
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Product Availability
3-5days
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$20000.00
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Product Overview
Product Name Anti-Human PCSK9 Monoclonal Antibody(Evolocumab); AMG 145
CAS1256937-27-5
AppearanceColorless to light yellow (Solution)
Storage conditionStore the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
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Product details

Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation.

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