依那妥组单抗
Enavatuzumab (Anti-TNFRSF12A / TWEAKR / CD266)
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Product Availability
3-5days
Price
$820.00
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Product Availability
3-5days
Price
$2400.00
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Product Availability
3-5days
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$4200.00
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Product Availability
3-5days
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$19500.00
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Product Overview
Product Name Enavatuzumab (Anti-TNFRSF12A / TWEAKR / CD266)
CAS1062149-33-0
Storage conditionStore at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.
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Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK) . TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo.

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History
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