Product Name | Etrolizumab (Anti-Integrin α4β7) (ITGA4 & ITGB7) |
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CAS | 1044758-60-2 |
Storage condition | Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light. |
Etrolizumab (rhuMAb Beta7) is a gut-selective, anti- β7 integrin monoclonal antibody. Etrolizumab is specific targeting of the β7 subunit of α4β7 and αEβ7 integrins with K i values of 18 nM and 1800 pM for Human α4β7 and Human αEβ7-293, respectively. Etrolizumab can be used in research of inflammatory bowel disease (IBD).
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