埃万妥单抗
Anti-Human EGFRxMET Bispecific Antibody(Amivantamab; JNJ-61186372)
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Product Name Anti-Human EGFRxMET Bispecific Antibody(Amivantamab; JNJ-61186372)
CAS2171511-58-1
Storage condition-20°C for 3 years | In solvent: -80°C for 1 year
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Amivantamab (JNJ-61186372) is a fully human EGFR-MET bispecific antibody that combats resistance in NSCLC through multifaceted mechanisms: ligand blockade, receptor degradation, and immune cell activation, including ADCC and trogocytosis. This innovative approach targets both primary and acquired resistance, offering a new therapeutic avenue for patients with EGFR and MET aberrations.

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History
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