(3-氧代-1,3-二氢异苯并呋喃-1-基)膦酸二甲酯
(3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phosphonic acid dimethyl ester
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Product Name (3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phosphonic acid dimethyl ester
CAS61260-15-9
FormulaC10H11O5P
MW242.17
AppearanceOff-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is a reagent used in the synthesis of 4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one, an inhibitor of both PARP-1 AND PARP-2 that shows standalone activity against BRCA1-deficient breast cancer cell lines.

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History
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