Product Name | (3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phosphonic acid dimethyl ester |
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CAS | 61260-15-9 |
Formula | C10H11O5P |
MW | 242.17 |
Appearance | Off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate is a reagent used in the synthesis of 4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one, an inhibitor of both PARP-1 AND PARP-2 that shows standalone activity against BRCA1-deficient breast cancer cell lines.
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