Product Name | Fmoc-Leu-OH; Fmoc-L-Leu-OH; Fmoc-L-Leucine |
---|---|
CAS | 35661-60-0 |
Formula | C21H23NO4 |
MW | 353.41 |
Appearance | White to off-white powder |
Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity
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